Gudrun Brüne was born in Berlin in 1941. From 1961 to 1966 she studied at the Academy of Fine Arts in Leipzig. There she met Bernhard Heisig, in whose studio she worked for a time as an assistant and whom she later married. From 1977 to 1999 she taught painting and graphic arts at the Burg Giebichenstein University of Arts in Halle (Saale). She received art awards from the Freier Deutscher Gewerk­schaftsbund and the GDR. Brüne lives and works in Havelland (Brandenburg).